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The function of Vav protein in immune system / 国际儿科学杂志
International Journal of Pediatrics ; (6): 47-50, 2020.
Article in Chinese | WPRIM | ID: wpr-862922
ABSTRACT
Vav-family proteins are guanosine nucleotide exchange factors (GEFs) and one of RhoGEFs family numbers.Vav proteins can influence cell signaling transduction,cytoskeleton recombination and adherence migration in special cells by RhoA,RhoG and Rac-1 pathway.There are 80 kinds of RhoGEFs in mammalian cell.Vav proteins play an important role in hematological system,nervous system,cardiovascular system and immune system.So the function of vav protein in immune system was reviewed in this paper.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Pediatrics Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Pediatrics Year: 2020 Type: Article