Research progress in material surface microstructure regulating osteoclastic cells / 国际生物医学工程杂志
International Journal of Biomedical Engineering
;
(6): 244-249, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-863228
ABSTRACT
The development of bone tissue engineering puts forward higher requirements for scaffold materials. Based on the theory of complete regeneration in regenerative medicine, bone graft substitutes are required to be osteoinducible, and to be degraded by osteoclasts and replaced with new bone tissue. Absorbable scaffold materials can be degraded by osteoclasts, and their physical and chemical properties also affect the behavior of osteoclasts. The surface microstructure of the materials is the key to initiating osteoinduction, and it has an important influence on the behavior of osteoclasts. In addition, the surface roughness of the materials can enhance the functional activity of osteoclasts within a certain range. In this paper, the research progress in material surface microstructure regulating osteoclastic cells were reviewed, in order to further explore its mechanism of action, and provide a reference for the preparation of better performance tissue engineering scaffold materials.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Biomedical Engineering
Year:
2020
Type:
Article
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