Application of FOLFIRINOX regimen in conversion therapy of unresectable pancreatic cancer / 国际外科学杂志

ABSTRACT

Pancreatic cancer is a common malignant tumor of the digestive system with high degree of malignancy and difficulty in diagnosis.Patients with unresectable pancreatic cancer can regain the opportunity to receive surgical treatment with a combination of treatments known as conversion therapy. FOLFIRINOX regimen (Oxaliplatin+ Irinotecan+ 5-Fluorouracil+ Calcium folate) is an effective convesion therapy for unresectable pancreatic cancer, increasing surgical resection rate and prolongation of survival.This review aims to review the application of the FOLFIRINOX regimen in conversion therapy of unresectable pancreatic cancer.