Research progress and prospect of different components of exosomes in breast cancer / 国际外科学杂志

ABSTRACT

Exosomes play an important role in the early diagnosis of various diseases, and it is a research hotspot in recent years. Exosomes are vesicles with a diameter of 30 to 100 nm secreted by cells, which widely exist and distribute in various body fluids. They carry a large number of specific proteins and functional substances, and participate in the transmission of intercellular substances and information, including tumor metastasis, immunity, cardio cerebral vascular, stem cell therapy, as well as immune regulation, targeted drug delivery, tissue damage repair, etc., forming It is an ideal biomarker. In this paper, the latest research progress of the main components of exosomes (miRNA, protein, mRNA, lncRNA, piRNA, circRNA, DNA and so on) in breast cancer in recent years is reviewed.