Meta-analysis of hypertension as a risk factor of cerebrovascular disorders in Koreans
Journal of Korean Medical Science
;
: 2-8, 2001.
Article
in English
| WPRIM
| ID: wpr-86347
ABSTRACT
This study was conducted to integrate the results of previous studies which evaluated hypertension as a risk factor for cerebrovascular disorders (CVD) in Koreans. We retrieved the Korean literature using a manual search and the English literature using the MEDLINE database concerning the relationship between hypertension and CVD in Koreans from 1980 to 1997. The overall effect size of hypertension as a risk factor of CVD was represented by common odds ratio (OR). Before the integration of each effect size, a heterogeneity test and a sensitivity test was conducted. The materials were nine published epidemiologic studies with a total of 2,271 cases of CVD. The common ORs (95% confidence interval) of overall CVD, hemorrhagic CVD and ischemic CVD associated with hypertension were 4.10 (3.56-4.71), 6.56 (4.92-8.80) and 3.28 (2.77-3.90), respectively. Thus, the common OR of hemorrhagic CVD associated with hypertension was significantly higher than that of overall or ischemic CVD. This suggests that hypertension is an important risk factor for overall CVD and its subtypes in Koreans. Due to the lack of reliable prospective studies, however, longitudinal study is required in this area.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Randomized Controlled Trials as Topic
/
Risk Factors
/
Stroke
/
Hypertension
Type of study:
Controlled clinical trial
/
Etiology study
/
Observational study
/
Risk factors
/
Systematic reviews
Limits:
Humans
Language:
English
Journal:
Journal of Korean Medical Science
Year:
2001
Type:
Article
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