Mechanism of long non-coding RNA GHET1 in tumors of the digestive system / 国际肿瘤学杂志

ABSTRACT

Gastric cancer highly expressed transcript 1 (GHET1) is first found in gastric cancer and is a long non-coding RNA (lncRNA). GHET1 is located on chromosome 7q36.1, and is highly expressed in many tumors. High expression of GHET1 is closely related to poor prognosis. Studies have found that GHET1 is involved in regulating many physiological and pathological processes of the body through interaction with microRNAs (miRNAs) or proteins, especially in digestive system tumors, and is expected to become a valuable tumor marker and therapeutic target in the future.