Orthogonal test method to optimize the extraction process of Xiaoaiping capsules / 国际中医中药杂志
International Journal of Traditional Chinese Medicine
;
(6): 1119-1124, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-863736
ABSTRACT
Objective:
To optimize water extraction and alcohol precipitation technology of Xiaoaiping capsules.Methods:
With the content of Tenacissoside G and dry extract yield rate as the index, to investigate the effects of extraction times, extraction time and the amount of water on extraction technology by orthogonal test; and investigate the influence of the concentration of alcohol precipitation, the relatively density of concentrated liquid and storage time on alcohol precipitation technology by orthogonal test.Results:
The optimal water extraction technology was 6-fold water, decocting 3 times for 1.5 h each time. The optimal alcohol precipitation technology was concentrating the water extraction to the density of 1.15 (60 ℃), and add alcohol after cooling with 70% alcohol standing for 12 hand then removing the precipitation.Conclusions:
The optimized water extraction and alcohol precipitation process is stable, feasible and reproducible, which could provide reference for the extraction and purification of Xiaoaiping capsules.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Traditional Chinese Medicine
Year:
2020
Type:
Article
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