Updates on invasive pneumococcal disease′s in children and their pathogenic strains / 中华实用儿科临床杂志

ABSTRACT

Streptococcus pneumoniae is a common pathogen of infections in children, and can cause invasive and non-invasive diseases.The invasive diseases cause extremely heavy burden and particularly serious consequences to patients.In this article, the recent progress in the epidemiology, disease distribution, and strain changes of invasive pneumococcal diseases was reviewed, which provided reference for vaccine design, immunization program implementation and clinical treatment.