Research progress of peripheral blood cell parameters in clinical prediction of Kawasaki disease / 中华实用儿科临床杂志

ABSTRACT

Peripheral blood cell parameters such as neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and the mean platelet volume-to-lymphocyte ratio are markers of systemic inflammation, which can predict the occurrence, efficacy and prognosis of cardiovascular diseases, tumors, systemic inflammatory reactions and other di-seases.Current studies show that neutrophil percentage, serum albumin, C-reactive protein, erythrocyte hematocrit, platelet count, serum sodium, total bilirubin, and N-terminal pro B type natriuretic peptide (NT-proBNP) are co-mmon independent risk factors of coronary artery lesions or immunoglobulin resistance in children with Kawasaki disease.New research suggests that peripheral blood cell parameters have predictive value for coronary artery lesions and immunoglobulin in children with Kawasaki disease.Peripheral blood cell parameters have wide applications due to the cheap and simple routine blood test.In this paper, the research progress in predicting coronary artery disease and immunoglo-bulin resistance in children with Kawasaki disease by peripheral blood cell parameters was reviewed.