Progress in diagnosis and treatment of children with primary membranous nephropathy / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics
;
(24): 1310-1312, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-864228
ABSTRACT
As an immune complex-mediated renal disease, membranous nephropathy(MN) can occur at all ages.Primary membranous nephropathy(PMN) can lead to end-stage renal disease although it is not common in children.Antibodies against M-type phospholipase A2 receptor / thrombospondin type-1 domain-containing 7A are initially detected in adult PMN, and also present in children and adolescents with PMN.These antibodies serve as useful biomarkers to diagnose and monitor PMN.Rituximab has been successfully used in the treatment of adult PMN, and is possibly effective in children with PMN as well.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Chinese Journal of Applied Clinical Pediatrics
Year:
2020
Type:
Article
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