Adenovirus infection and respiratory-related diseases in children / 中华实用儿科临床杂志

ABSTRACT

Adenovirus (AdV) infection has been prevalent in the world for more than 60 years, with occasional local outbreaks and epidemics.Through gene recombination, new genotypes of AdV have been discovered continuously, showing varying pathogenic characteristics.Genotypes prevalent in different countries or regions are diverse.AdV infection can cause respiratory, gastrointestinal, urinary and eye diseases.The incidence and mortality of AdV respiratory tract infection are high in children, and there are many severe cases.At present, no antiviral drug approved to treat AdV infection.Severe AdV pneumonia in children has a fatality rate exceeding 50%, which becomes a difficult problem in the treatment of severe pneumonia in intensive care unit.This paper reviews the research progress of AdV infection, and summarizes the related research of respiratory system diseases in children with AdV infection, so as to improve the understanding of children with AdV infection related respiratory diseases.