Research progress of milk protein allergy in neonates / 中国小儿急救医学

ABSTRACT

Cow′s milk protein allergy refers to the immune response of the body to some protein molecules in milk.The mechanism of milk protein allergy includes gut barrier destruction, intrauterine sensitization, breast milk transmission, heredity, environmental factors and gastrointestinal surgery.Most of the clinical symptoms are digestive tract, and the severe cases include hypoalbuminemia, growth retardation, even shock and circulatory failures.Some cases are accompanied by skin and mucous manifestations.The diagnosis needs to be evaluated clinically and made clear according to the history, clinical manifestations and laboratory examination.Milk protein avoidance is the most effective treatment at present.The application of probiotics can prevent allergy.