The prevalence of thyroid nodule in adults in different water iodine areas of Shanxi Province / 中华地方病学杂志

ABSTRACT

Objective:To master the prevalence of thyroid nodule in adults in different water iodine areas and to explore the association between high iodine intake through drinking water and thyroid nodule prevalence.Methods:Xiwenzhuang Village of Taiyuan City was selected as iodine-adequate area, and Gaoche Village and Maxi Village of Wenshui County as high-iodine area and low-iodine area, respectively, in Shanxi Province. Questionnaire surveys were conducted, thyroid ultrasound was used and urinary iodine levels were determined of residents aged 18 to 65 years. Analysis of the prevalence of thyroid nodules in adults in different wated iodine areas.Results:A total of 868 person were investigated, including 286 in high-iodine area, 270 in iodine-adequate area and 312 in low-iodine area. The medians urinary iodine in high, adequate and low iodine areas were 418.7, 218.5 and 127.1 μg/L, respectively, and the differences were statistically significant ( H = 289.70, P < 0.05). The detection rate of thyroid nodule in adults with high, adequate and low iodine levels were 31.1% (89/286), 27.4% (74/270) and 19.2% (60/312), respectively, the differences were significant statistically among three groups (χ 2 = 11.65, P < 0.05). The detection rates of solitary nodule in adults were 17.8% (51/286), 14.1% (38/270), and 13.1% (41/312), respectively, the differences were not significant statistically among the three groups (χ 2 = 2.83, P > 0.05). The detection rate of multiple nodules in adults were 13.3% (38/286), 13.3% (36/270), and 6.1% (19/312), respectively, the differences were significant statistically among the three groups (χ 2 = 10.89, P < 0.05) high-iodine area and iodine-adequate area have higher detection rates than low-iodine area ( P < 0.05). The thyroid nodules were mainly the cyst nodules in high-iodine area. Conclusions:The detection rate of thyroid nodule in adults is the lowest in adequate iodine nutrition level. More iodine intake is probably a risk factor for thyroid multiple nodules.