Risk factors of nosocomial infection after craniocerebral trauma / 中国基层医药

ABSTRACT

Objective:To analyze the risk factors of nosocomial infection after craniocerebral trauma.Methods:From June 2016 to June 2019, 314 patients with craniocerebral injury admitted to Dajiangdong Hospital were treated with surgical operation.According to whether infection occurred after operation, they were divided into infection group ( n=29) and uninfected group ( n=285). Multivariate logistic regression was used to analyze the risk factors of nosocomial infection after craniocerebral injury. Results:Of 314 patients with craniocerebral injury, 29 cases (9.24%) had postoperative nosocomial infection.Single factor analysis showed that there were no significant differences between the two groups in gender, hypertension and injury type (all P>0.05). The proportion of age>60 years old in the infected group (15.91%) was higher than that in the uninfected group (4.40%), the proportion of diabetes mellitus in the infected group(26.23%) was higher than that in the uninfected group (8.50%), the proportion of preoperative GCS score<8 points in the infected group(15.75%) was higher than that in the uninfected group (4.81%), and the proportion of operation time>10 d in the infected group(14.09%) was higher than that in the uninfected group (4.85%), invasive operation rate in the infected group(19.49%) was higher than in the uninfected group (3.06%), CSF leakage rate in the infected group(19.15%) was higher than in the uninfected group(5.00%), extraventricular drainage rate in the infected group(25.00%) was higher than than in the uninfected group (4.20%), the differences were statistically significant (χ 2=12.099, 11.706, 10.789, 5.954, 7.984, 23.720, 15.728, 29.726, all P<0.05). The logistic regression analysis showed that age>60 years old, complicated with diabetes mellitus, preoperative GCS score<8 points, operation time>3 h, hospital stay>10 d, invasive operation, CSF leakage and ventricular drainage were the risk factors of postoperative hospital infection. Conclusion:Nosocomial infection after craniocerebral trauma is affected by many factors, including age, diabetes mellitus, preoperative GCS score, operation time, hospitalization time, invasive operation, cerebrospinal fluid leakage and extraventricular drainage.