Effect of Shensong Yangxin capsule on hemorheology and cardiac function in patients with tachyarrhythmia / 中国基层医药

ABSTRACT

Objective:To study the efficacy of Shensong Yangxin capsule in the treatment of tachyarrhythmia and its effect on the hemorheology and cardiac function of patients.Methods:From June 2013 to June 2018, 86 patients with tachyarrhythmia who were treated in Taizhou Orthopedic Hospital were enrolled.The patients were divided into control group and observation group according to the random number table method, with 43 cases in each group.The patients in the control group were treated with amiodarone hydrochloride tablets, the patients in the observation group were treated with Shensong Yangxin capsule on the basis of the control group.After 8 weeks, the clinical efficacy, hemorheology and cardiac function of the two groups were compared and analyzed.Results:The total effective rate of the observation group was 93.02%(40/43), which was significantly higher than 76.74%(33/43) of the control group(χ 2=11.064, P<0.05). The plasma viscosity, fibrinogen and hematocrit in the observation group[(1.10±0.20)mPa·s, (1.69±0.36)g/L, (36.94±0.96)%] were lower than those in the control group[(1.51±0.38)mPa·s, (3.02±0.75)g/L, (45.15±1.06)%], the differences were statistically significant between the two groups( t=7.615, 9.463, 11.656, all P<0.05). After treatment, the LVDs and LVDd in the observation group[(39.02±4.68)mm, (53.16±6.42)mm] were significantly higher than those in the control group[(35.48±4.05)mm, (47.99±5.09)mm], the differences were statistically significant between the two groups( t=4.916, 5.064, all P<0.05). Conclusion:Shensong Yangxin capsule has significant therapeutic effect on patients with tachyarrhythmia, which can significantly improve the hemorheology and heart function of patients, and it is safe and worthy of promotion.