Influence of the surgery concept of rapid rehabilitation on the postoperative rehabilitation, immune function and nutritional status of patients with colorectal cancer undergoing laparoscopic radical surgery / 中国基层医药

ABSTRACT

Objective:To explore the effect of the surgery concept of rapid rehabilitation on the postoperative rehabilitation, immune function and nutritional status of patients with colorectal cancer undergoing laparoscopic radical surgery.Methods:From June 2017 to June 2019, 106 patients with colorectal cancer underwent laparoscopic radical surgery in the Affiliated Hospital of Shaoxing University of Arts and Sciences were divided into the observation group and the control group according to the random digital table method, with 53 cases in each group.The observation group adopted the surgery concept of rapid rehabilitation, while the control group adopted the surgery concept of conventional rehabilitation.The amount of intraoperative bleeding, postoperative complications and operation time were compared between the two groups.The recovery of gastrointestinal function, the changes of immune function and nutritional indicators were compared between the two groups.Results:There were no statistically significant differences in the amount of bleeding and operation time between the two groups(all P>0.05). The incidence of postoperative complications in the observation group was 5.66%(3/53), which was lower than 24.53%(13/53) in the control group(χ 2=7.361, P<0.05). The time of first anal exhaust[(2.14±0.32)d] and first eating[(1.85±0.42)d]in the observation group were shorter than those in the control group[(3.62±0.61)d and (2.79±0.36)d]( t=15.642, 12.371, all P<0.05). Three days after operation, the CD 3+ [(50.82±2.31)%], CD 4+ [(34.01±2.19)%]and CD 4+/CD 8+ (1.03±0.08) in the observation group were higher than those in the control group[(46.30±2.68)%, (30.26±2.05)% and (0.81±0.12)]( t=9.300, 9.101, 11.105, all P<0.05). The serum transferrin[(1.97±0.14)g/L]and prealbumin[(0.23±0.03)g/L] in the observation group were higher than those in the control group[(1.72±0.15)g/L and (0.18±0.03)g/L]( t=8.870, 8.580, all P<0.05). Conclusion:The surgery concept of rapid rehabilitation can promote the postoperative rehabilitation of patients with colorectal cancer, improve the immune function and nutritional status of patients, and has less complications.