Effect of laparoscopic radical operation for advanced colon cancer / 中国基层医药

ABSTRACT

Objective:To observe the clinical effect of laparoscopic radical operation for advanced colon cancer.Methods:From June 2015 to February 2019, 100 patients with advanced colon cancer diagnosed and treated in the People's Hospital of Xinzhou were randomly divided into two groups by coin toss method, with 50 cases in each group.The observation group received laparoscopic radical operation, while the control group received traditional laparotomy.The operation indicators, recovery after operation and the occurrence of the complications were compared between the two groups.Results:The bleeding volume and operation time of the observation group were (120.44±10.15)mL, (90.65±5.19)min, respectively, which of the control group were (154.69±15.44)mL and (130.66±4.18)min, respectively, the differences between the two groups were statistically significant( t=13.107, 42.454, all P<0.05). There was no statistically significant difference between the two groups in the number of lymphadenectomy( P>0.05). The postoperative recover eating time, postoperative recover exhaust time and hospitalization time in the observation group were (3.82±0.96)d, (3.01±0.26)d, (10.57±1.28)d, respectively, which were significantly shorter than those in the control group [(4.97±0.34)d, (3.99±0.12)d, (14.96±2.01)d], and the differences were statistically significant( t=7.984, 24.199, 13.026, all P<0.05). There was no statistically significant difference in the incidence of complications between the two groups( P>0.05). Conclusion:Laparoscopic radical operation for advanced colon cancer has the advantages of less bleeding, shorter operation time, faster postoperative recovery and better effect compared with open operation.