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Comparison of the clinical effect of platelet rich plasma and autogenous osteochondral transplantation in the treatment of talar cartilage injury / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy ; (12): 2097-2101, 2020.
Article in Chinese | WPRIM | ID: wpr-866574
ABSTRACT

Objective:

To evaluate the clinical effect of intra-articular injection of platelet rich plasma in the treatment of talar cartilage injury.

Methods:

From May 2017 to May 2019, 128 patients with talar cartilage injury who were treated in Marine Police Hospital of the Chinese People's Armed Police Force were selected as the study objects.According to the random number table method, they were divided into two groups, with 64 patients in each group.The control group was treated with autogenous osteochondral transplantation, and the study group was treated with autogenous platelet rich plasma intra-articular injection.The degree of pain response was compared between the two groups.The change of ankle function was evaluated, the degree of ankle dorsiflexion and plantar flexion were measured, and the complications after treatment were observed.

Results:

After treatment, the visual analogue scale(VAS) score of the study group[(2.41±0.34)points] was significantly lower than that of the control group[(3.57±0.45)points]( t=8.639, P<0.05). The ankle hind-foot scale(AOFAS) score of the study group[(88.73±6.68)points] was significantly higher than that of the control group[(82.35±6.41)points]( t=3.684, P<0.05). The overall excellent and good rate of ankle function of the study group(95.31%) was significantly higher than that of the control group(82.81%)(χ 2=5.133, P<0.05). In the study group, the ankle dorsiflexion[(24.83±3.31)°] and plantar flexion[(44.92±5.17)°] were significantly higher than those in the control group[(20.65±3.08)° and (39.61±5.27)°]( t=5.247, 4.083, all P<0.05). The overall incidence of complications in the study group(21.88%) was significantly lower than that in the control group(7.81%)(χ 2=5.006, P<0.05).

Conclusion:

Compared with autograft osteochondral transplantation, the intra-articular injection of platelet rich plasma can effectively alleviate the pain response of patients with talar cartilage injury, improve the ankle joint function and activity recovery level, and reduce the incidence of complications, which is worthy of clinical application.
Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Primary Medicine and Pharmacy Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Primary Medicine and Pharmacy Year: 2020 Type: Article