A Study of Lithogenic and Inhibitory Substances in 24-hour Fractionated Urine of Healthy Men / 대한비뇨기과학회지

ABSTRACT

Circadian rhythms of the substances related to lithogenesis such as volume, pH, creatinine, calcium, magnesium, uric acid, phosphorus, citrate and oxalate in urine of 10 healthy men who led method of urine sampling at 2 hours interval from 600 were evaluated to midnight and a 6 hours The urine volume, pH, excretory amounts and concentration of calcium, magnesium, uric acid, citrate and oxalate except creatinine and phosphorus in 24-hour fractionated urine were shown to increase during postprandial period between 800 and 1000 and between 2200 and midnight. The creatinine excretion was minimal variations in all fractionated urine. The phosphorus excretion was modestly pronounced about dinner, but low value between 1000 and noon. Therefore, almost lithogenic and inhibitory substances in urine were relatively increased after breakfast and dinner so that lithogenesis were thought to be intimately concerned with diet.