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Study on the safety and effectiveness of postpyloric feeding in elderly patients with severe diseases / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy ; (12): 2961-2965, 2020.
Article in Chinese | WPRIM | ID: wpr-866717
ABSTRACT

Objective:

To investigate the clinical efficacy and safety of postpyloric feeding in elderly patients with severe disease.

Methods:

From March 2017 to December 2019, 66 elderly severe patients hospitalized in Taishan Sanatorium of Shandong Province were selected in the study.The patients were divided into control group and observation group according the random digital table method, with 33 cases in each group.The control group received routine nasogastric tube feeding nutrition support, while the observation group received post pylorus feeding nutrition support.The feeding time of both two groups was 14 days.The nutritional status, improvement and complications of the two groups were observed.

Results:

On the 14th day after feeding, the total serum protein(TP), albumin(ALB), transferrin(TF), prealbumin(PA) in the observation group were (62.75±4.22)g/L, (35.38±2.63)g/L, (2.09±0.13)g/L, (221.52±26.62)g/L, respectively, which were higher than those in the control group [(54.53±4.16)g/L, (32.34±2.83)g/L, (1.85±0.10)g/L, (197.85±25.73)g/L]( t=7.969, 4.520, 8.406, 3.673, all P<0.05). On the 3rd, 7th and 14th day after feeding, the ApacheⅡ scores of the observation group were (14.04±2.17)points, (10.95±2.21)points, (8.95±2.21)points, respectively, which were significantly lower than those of the control group [(15.98±2.45)points, (13.75±2.25)points, (10.75±2.25)points]( t=3.405, 5.100, 3.279, all P<0.05). The incidences of vomiting, gastric retention, dominant aspiration and aspiration pneumonia in the observation group were 3.03%(1/33), 12.12%(4/33), 0.00%(0/33), 12.12%(4/33) , respectively, which were significantly lower than those in the control group [18.18%(6/33), 33.33%(11/33), 12.12%(4/33), 33.33%(11/33)](χ 2=3.995, 4.227, 4.258, 4.227, all P<0.05).

Conclusion:

Postpyloric feeding used in elderly patients with severe illness can improve the nutritional status and condition of patients, and reduce the incidence of complications such as gastric retention and aspiration pneumonia.It has high efficacy and safety.
Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Primary Medicine and Pharmacy Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Primary Medicine and Pharmacy Year: 2020 Type: Article