Advance of extracorporeal membrane oxygenation therapy in cardiac arrest caused by acute poisoning / 中华危重病急救医学

ABSTRACT

Acute poisoning induced cardiac arrest (APCA) is an acute circulatory failure caused by severe poisoning, which is characterized by complicated mechanisms, limited treatment methods and poor prognosis. Recently, emerging evidence has demonstrated that extracorporeal membrane oxygenation (ECMO) could be a promising tool that may benefit the patients with APCA refractory to conventional resuscitation methods. However, further well-designed studies are needed to evaluate and resolve the emerged problems during the process of ECMO therapy in patients with APCA, such as population indications, optimal conditions, cost-effectiveness, etc. Therefore, this article reviews the epidemiology and mechanism of APCA, and the experimental and clinical studies of the application of ECMO in APCA, in order to explore the clinical value of ECMO in the treatment of APCA patients.