Effects of sleep deprivation and circadian rhythm on inhibition control performance of college students / 中华行为医学与脑科学杂志

ABSTRACT

Objective:To explore the effects of 36-hour acute total sleep deprivation and day rhythm on the inhibition and control performance of college students.Methods:Thirty-three college students were subjected to two factors (sleep conditions acute sleep deprivation, normal sleep) × 4 (rhythm time 13∶00, 15∶00, 17∶00, 19∶00) within-subject experiments, using Go/No-go task to measure the ability to inhibit control, and asking individuals to report nine levels of subjective sleepiness and fatigue. Descriptive statistics and repeated ANOVA were performed with R 3.6.2 and Jamovi 1.2.2.Results:The hit rate was statistically significant in the interaction between sleep condition and circadian rhythm condition ( F(2.54, 81.22)=4.41, P<0.01). The simple effect analysis found that under the condition of sleep deprivation, the hit rate at 17∶00 (0.92±0.07) was significantly higher than that at 13∶00 (0.84±0.11) and 15∶00 (0.88±0.12), and the differences were statistically significant ( P<0.05). The differences of discrimination index d' under sleep condition was statistically significant ( F(1, 32)=27.55, P<0.01), and this under sleep deprivation condition (2.36±0.82) was lower than this under normal sleep condition (2.98±0.76), and the difference was statistically significant ( P<0.01). The hit reaction time, false reaction time, subjective sleepiness level and fatigue level under sleep deprivation condition ((430.11±60.72)ms, (429.27±126.23)ms, (6.67±1.37), (5.30±1.75)) were greater than those under the normal sleep condition ((386.56±48.89)ms, (361.64±60.85)ms, (5.39±1.19), (3.31±1.46)), and the difference were statistically significant ( F(1, 32)=62.52, 31.17, 45.74, 68.97, all P<0.01). The difference of hit reaction time ( F(3, 96)=3.66) under the condition of circadian rhythm was statistically significant ( P<0.05). The hit reaction time at 13∶00 (416.75±60.21)ms was higher than 19∶00 (399.25±59.01)ms, and the difference was statistically significant ( P<0.01). Conclusion:Individuals' inhibition control and subjective fatigue were significantly reduced after sleep deprivation, and inhibition control was partially modulated by circadian rhythm.