Recent advances of aggregation-induced emission in tumor diagnosis and therapy / 中华核医学与分子影像杂志

ABSTRACT

Aggregation-induced emission (AIE) refers to an uncommon phenomenon that some fluorogens are weakly emissive in solution but become intensely florescent in aggregated state. Fluorogens with the characteristics of AIE are called AIEgens. Traditional dyes often suffer from a common photophysical phenomenon named aggregation-caused quenching (ACQ). As an anti-ACQ phenomenon, AIE shows great potential in biomedical applications. In this paper, the flurescence mechanism and characteristics of AIE are summarized, and the recent advances of aggregation-induced emission in tumor diagnosis and therapy is reviewed.