Preliminary comparison between cerebral vascular hemodynamic indexes and revised Framingham stroke risk profile in predicting the risk of stroke among physical examiners / 中华健康管理学杂志

ABSTRACT

Objective:To compare cerebral vascular hemodynamic indexes (CVHI) and revised Framingham stroke risk profile (FSP) in predicting the risk of stroke among physical examiners.Methods:A total of 1 049 individuals were enrolled from the Health Management Center, Jiangsu Province Hospital during January 2019 and January 2020. Correlation analysis was carried out to confirm the correlations of risk factors of stroke with CVHI accumulative score and FSP. Multivariate logistic regression analysis was performed to evaluate the influence of CVHI classification, hypertension, diabetes and smoking on the 10-year risk of stroke evaluated by FSP.Results:In this study, the number of people whose CVHI accumulative score was less than 75 was 163 (15.54%) and the number of people whose 10-year probabilities of stroke was greater than or equal to 6% was 202 (19.26%). The CVHI accumulative score was negatively related with FSP ( r=-0.284, P<0.001). The result demonstrated that the CVHI classification, hypertension, diabetes and smoking were independent predictors for the 10-year risk of stroke evaluated by FSP. Conclusions:The proportion of individuals with stroke risk in medical examination population evaluated by CVHI is lower than by FSP. Combination of CVHI and FSP can effectively predict the risk of stroke among physical examiners.