The application of MRI combined with diffusion tensor imaging in disease evaluation of elderly patients with craniocerebral injury / 中华老年医学杂志

ABSTRACT

Objective:To assess the value of magnetic resonance imaging(MRI)combined with diffusion tensor imaging(DTI)in disease evaluation of elderly patients with craniocerebral injury.Methods:A total of 80 elderly patients with craniocerebral injury from January 2017 to November 2019 in Shangqiu First People's Hospital were included and retrospectively analyzed.Based on the degree of craniocerebral injury assessed using relevant standards combined with the Glasgow score(GCS), patients with mild injury were included in the mild group(n=33), and the rest were included in the moderate and severe group(n=47). Another 40 healthy elderly persons from the same period were enrolled in the control group.All subjects underwent head MRI on the day of admission.Baseline data were recorded.The performance of each sequence of MRI examination and the number of detected bleeding lesions in patients were recorded.The value of MRI combined with DTI on craniocerebral injury evaluation was analyzed.Results:There was no significant difference in baseline data between the groups(all P<0.05). The number of bleeding lesions in the frontal lobe, temporal lobe, corpus callosum, basal ganglia, thalamus, brainstem and cerebellum was lower in the mild group than in the moderate and severe group( t=21.479, 19.270, 48.901, 23.003, 10.112, 16.108 and 13.934, all P<0.001). The FA and ADC values of the frontal lobe white matter, temporal lobe white matter, corpus callosum, pons, left and right sides of the internal capsule had significant differences between the three groups( FFA=93.570, 449.338, 58.371, 126.061, 35.422, 15.002, 140.938 and 187.958, F ADC=97.790, 59.383, 58.661, 60.141, 31.042, 40.147, 57.696, 58.011, 30.962 and 31.741, all P<0.001), except those of the left and right sides of the pons( F=1.988 and 1.732, P=0.142 and 0.181), and the moderate and severe group had the lowest FA and ADC values, followed the mild group and the control group. Conclusions:MRI combined with DTI scan can comprehensively and clearly show intracranial lesions in elderly patients with craniocerebral injury.The more bleeding lesions detected by MRI, the lower the FA value or ADC value in the observed area by DTI examination, indicating the more serious injury in patients.