The association between serum uric acid and cognitive dysfunction / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
; (12): 437-441, 2020.
Article
in Zh
| WPRIM
| ID: wpr-870046
Responsible library:
WPRO
ABSTRACT
As the aging process accelerates, cognitive dysfunction has become a significant public health problem. Recently, oxidative stress has been recognized as a critical factor contributing to the pathogenesis of cognitive dysfunction. Therefore, uric acid, as an important antioxidant in vivo, might correspondingly play cognitive protection roles. However, uric acid was regarded as a risk factor for cognitive deterioration in some studies. The uric acid paradox, together with the pathophysiological differences between cognitive disorders, adds to the complexity of their association. So far, the impact of uric acid on cognitive function has been debated. This article tried to review the impact of uric acid on different cognitive disorders and to discuss the possible mechanisms.
Full text:
1
Index:
WPRIM
Type of study:
Risk_factors_studies
Language:
Zh
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2020
Type:
Article