Classification of hemangiomas and vascular malformations / 中华皮肤科杂志

ABSTRACT

Classification of hemangiomas and vascular malformations has gone through centuries of history from the most primitive morphological classification to the current biological classification. In 2018, the International Society for the Study of Vascular Abnormalities (ISSVA) refined and supplemented the classification of vascular tumors based on the 1996 and 2014 editions, and added 15 rare vascular tumors; for vascular malformations, the 2018 ISSVA classification reclassified the subtypes of capillary malformations, renamed "verrucous hemangioma" as "verrucous vascular malformation", added "limb capillary malformation with congenital non-progressive limb overgrowth", "CLAPO syndrome", PIK3CA-related hyperproliferative diseases, and so on. This review elaborates the primitive classification, traditional classification and modern classification of hemangiomas and vascular malformations, compares the similarities and differences among the 1996, 2014 and 2018 ISSVA classifications, and discusses the significance of the modern classification of hemangioma and vascular malformations for diagnosis and treatment.