Tuberculosis-associated panniculitis / 中华皮肤科杂志

ABSTRACT

The causes of panniculitis are various and complex, and infection is one of the important causes. Streptococcal infection is the most common cause in Europe and the United States with a low incidence of tuberculosis. In areas with a high incidence of tuberculosis such as China, Mycobacterium tuberculosis infection is an important cause of panniculitis, which commonly manifests as erythema induratum of Bazin and erythema nodosum. Erythema induratum of Bazinis is most closely related to tuberculosis, often clinically manifests as nodules, plaques and ulcers on the flexor aspect of the lower extremities, and pathologically manifests as lobular panniculitis. Erythema nodosum can be considered as an early symptom of tuberculosis, and serves as a predictive indicator of tuberculosis. It often manifests as erythema, nodules and few ulcers on the extensor aspect of both lower limbs, and is pathologically characterized by septal panniculitis. Antituberculosis treatment often yields favorable outcomes in patients with erythema induratum of Bazin or erythema nodosum. Therefore, clarifying the relationship between Mycobacterium tuberculosis and panniculitis is of great significance to the treatment and prognosis of panniculitis, especially in areas with a high incidence of tuberculosis.