Progress in diagnosis and treatment of DNA methylation and pulmonary fibrosis / 中华检验医学杂志
Chinese Journal of Laboratory Medicine
; (12): 91-95, 2020.
Article
in Zh
| WPRIM
| ID: wpr-871850
Responsible library:
WPRO
ABSTRACT
Pulmonary fibrosis is the late stage of many lung diseases. It′s a pathological process with excessive deposition of extracellular matrix, tissue scar formation and lung tissue remodeling. Recently, DNA methylation has been demonstrated to involve in organ fibrosis, includingpulmonary, liver, renal fibrosis and so on. DNA methylation plays an important role in clinical diagnosis and treatment. This article reviews the role of DNA methylation in the development of pulmonary fibrosis and discusses thepathogenic mechanism of pulmonary fibrosis and new anti-fibrotic strategy.
Full text:
1
Index:
WPRIM
Type of study:
Diagnostic_studies
Language:
Zh
Journal:
Chinese Journal of Laboratory Medicine
Year:
2020
Type:
Article