The values of complement system in the diagnosis, treatment and prognosis of urticarial vasculitis / 中华检验医学杂志

ABSTRACT

Urticarial vasculitis (UV) is a type Ⅲ hypersensitivity reaction mediated by immune complexes, and it demonstrates leukocytoclastic vasculitis pathologically. Complement activation plays a crucial role in UV development. Serum complement level can not only be helpful for UV classification but also be of great value in predicting illness severity, treatment response and prognosis. Therefore, attention should be paid to complement measurement in the diagnosis and treatment of UV.