Survival mechanism of free bone graft in calvarial defects using a murine model / 中华医学美学美容杂志
Chinese Journal of Medical Aesthetics and Cosmetology
;
(6): 268-271, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-872166
ABSTRACT
Objective:
To study the mechanism of free bone graft survival in calvarial defects.Methods:
We simulated the bone autograft reconstruction through transplanting green fluorescent protein (GFP) mice' cranium to the nude mice' calvarial bone defects. Then gross and histological evaluation were performed to calculate BTA (%) and GFP (%) in graft bone.Results:
The results showed that the green fluorescence was getting disappeared from 4 to 24 weeks' post-operation. However, a small amount of green fluorescence remained at 24 weeks' post-operation (6.69% of the positive control group). In addition, the gross and histological evaluation indicated that the grafted bone survived well at different time points.Conclusions:
The survival mechanism of free bone graft in cranium mainly relies on creeping substitution assisted with bony regeneration.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Medical Aesthetics and Cosmetology
Year:
2020
Type:
Article
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