Biometric Characteristics in Eyes with Pseudoexfoliation Syndrome and Eyes with Acute Angle Closure

ABSTRACT

Purpose@#To investigate the biometric characteristics of eyes with pseudoexfoliation syndrome (PEX) according to the anterior chamber depth (ACD) by comparing them to patients with acute angle closure (AAC) and a control group. @*Methods@#A total of 130 eyes of 121 subjects (PEX, 49 eyes; AAC, 28 eyes; and control, 53 eyes) were included in the study. Axial length (AL), ACD, and lens thickness (LT) were measured with an IOL Master® 700 (Carl Zeiss Meditec, Jena, Germany). The total PEX (PXall) group was divided into a PEX with deep ACD group (PXd) and a shallow ACD group (PXs) based on an ACD of 2.70 mm. We compared the biometric results among the PXall, PXd, PXs, AAC, and control groups. @*Results@#There was no significant difference in AL between the PXall and control groups; however, the PXall group had a shallower ACD and thicker lenses. After dividing the PXall group into two groups based on ACD, the PXd group showed no difference in LT compared to the control group (p = 0.113). The LT of the PXs group was thicker than those of the PXd and control groups (p < 0.001 and p < 0.001, respectively). The PXs group had longer ALs than the AAC group (p = 0.025); however, there was no difference in LT or in the ratio of LT to AL (p = 0.222 and p = 0.076, respectively). @*Conclusions@#The biometric characteristics were different in eyes with PEX based on ACD. PEX patients with deep ACDs showed no difference in biometry compared to the control group; however, PEX patients with shallow ACDs showed characteristics of a thick LT, similar to AAC patients. There was no difference in the ratio of LT to AL among groups.