NLRP6 as a Negative Regulator of Innate Immunity
Journal of Bacteriology and Virology
;
: 64-66, 2013.
Article
in English
| WPRIM
| ID: wpr-87590
ABSTRACT
Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) play important role in immune responses by regulating nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB), type I interferon and inflammasomes. Nod-like receptor pyrin domain-containing protein 6 (NLRP6) is vital for protection of mice from colitis and colorectal tumorigenesis. However, the role of NLRP6 in microbial infection remains unclear. NLRP6 was recently reported as negative regulator of inflammatory signaling and demonstrated that how it hinders clearance of bacterial pathogens.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
B-Lymphocytes
/
Interferon Type I
/
Cell Transformation, Neoplastic
/
Colitis
/
Cytoskeletal Proteins
/
Inflammasomes
/
Immunity, Innate
/
Listeria monocytogenes
Limits:
Animals
Language:
English
Journal:
Journal of Bacteriology and Virology
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS