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Progress of researches on the involvement of indoleamine 2, 3-dioxygenase in regulation of parasite-host immune interactions / 中国血吸虫病防治杂志
Chinese Journal of Schistosomiasis Control ; (6): 209-212, 2020.
Article in Chinese | WPRIM | ID: wpr-876716
ABSTRACT
Indoleamine 2, 3-dioxygenase (IDO) is an important immunoregulatory enzyme, which mediates immune effects by depleting tryptophan and producing multiple metabolites. Recently, the studies on the immune function of IDO have been mostly restricted in tumors and autoimmune diseases. Nevertheless, there are few studies pertaining to the role of IDO in parasitic diseases, notably in parasite-host immune interactions. This review mainly describes IDO-mediated immunoregulatory effects and its regulation of parasite-host interactions, so as to provide insights into the development of immune intervention schemes against parasitic diseases.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Schistosomiasis Control Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Schistosomiasis Control Year: 2020 Type: Article