Progress in the study of signal transduction pathways related to the pathogenesis of glaucoma / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
;
(12): 1021-1024, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-876748
ABSTRACT
@#Glaucoma is the leading cause of irreversible vision loss in the world. Drugs and surgery can be used to control intraocular pressure, however, they can't reverse the apoptosis of retinal ganglion cells effectively. With the development of genetics and molecular biology, a large amount of research on the pathogenesis of glaucoma has been conducted. This review discusses the potential role of Rho/ROCK, TGF-β/Smad, PI3K/Akt, Nrf2/Keap1/ARE and BDNF/TrkB signaling pathways in the pathogenesis of glaucoma, and expects to provide new ideas and methods for the treatment of glaucoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
International Eye Science
Year:
2021
Type:
Article
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