Epidemiological analysis of human papillomavirus infection in women of childbearing age in Shaanxi / 公共卫生与预防医学

ABSTRACT

Objective To explore the epidemiology of human papillomavirus infection in women of childbearing age in Shaanxi Province. Methods A stratified random sampling method was used to select 16705 patients under childbearing age in Shaanxi from January 2015 to January 2020, and 857 healthy patients who had physical examination during the same period were selected as the control group. The general information of patients was obtained through questionnaire survey, and the risk factors were analyzed by single factor and multivariate logistic analysis. Results The detection rate of human papillomavirus infection in 16705 cases was 2570 (15.38%), of which 1972 cases of high-risk type (11.80%) were higher than 598 cases (3.58%) of low-risk type (χ2 795.77, P 2 259.08, P <0.001).The proportions of younger than 30 years old, sexual life ≥3 times/week, no condoms, cervical erosion, and smoking were higher in high-risk human papillomavirus infection group than the control group (P<0.05). After multivariate logistic regression analysis, the results showed that the frequency of sexual life and the greater degree of cervical erosion were independent risk factors for high-risk human papillomavirus infection [OR (95% CI) 3.112 (1.607~7.702), 4.209 (2.338~ 12.526, P<0.05], the use of condoms is a high-risk protective factor for human papillomavirus infection [OR(95%CI) 0.674 (0.578~0.699, P<0.05]) Conclusion The frequency of sexual life and the degree of cervical erosion are high in women of childbearing age in Shaanxi. The use of condoms can effectively prevent human papillomavirus infection. Reasonably formulating effective intervention measures and vigorously publicizing the knowledge of human papillomavirus prevention and treatment is the key to reducing human papillomavirus infection in women of childbearing age in Shaanxi.