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Bioconversion of methane by metabolically engineered methanotrophs / 生物工程学报
Chinese Journal of Biotechnology ; (12): 816-830, 2021.
Article in Chinese | WPRIM | ID: wpr-878598
ABSTRACT
Due to abundant availability of shale gas and biogas, methane has been considered as one of the most potential carbon sources for industrial biotechnology. Methanotrophs carrying the native methane monooxygenase are capable of using methane as a sole energy and carbon source, which provides a novel strategy for reducing greenhouse gas emission and substituting edible substrates used in bioconversion processes. With the rapid development of genetic engineering tools and biosynthesis techniques, various strategies for improving the efficiency of methane bioconversion have been achieved to produce a variety of commodity bio-based products. Herein, we summarize several important aspects related with methane utilization and metabolic engineering of methanotrophs, including the modification of methane oxidation pathways, the construction of efficient cell factories, and biosynthesis of chemicals and fuels. Finally, the prospects and challenges of the future development of methane bioconversion are also discussed.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Oxidation-Reduction / Biotechnology / Biofuels / Metabolic Engineering / Methane Language: Chinese Journal: Chinese Journal of Biotechnology Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Oxidation-Reduction / Biotechnology / Biofuels / Metabolic Engineering / Methane Language: Chinese Journal: Chinese Journal of Biotechnology Year: 2021 Type: Article