Predictive Biomarkers of Immune-related Adverse Events Induced by Checkpoint Inhibitors in Malignancies / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 825-830, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-878685
ABSTRACT
While immune checkpoint inhibitors(ICIs)are effective and promising treatments for a variety of malignancies,they also have safety concerns,especially the immune-related adverse events(irAEs).Unlike the side effects of traditional chemotherapy and targeted therapy,irAEs are adverse events caused by immune activation after ICIs treatment and thus may involve almost every system of the body.Therefore,biomarkers for predicting irAEs after ICIs treatment are urgently needed.Here we review the currently available predictive biomarkers of irAEs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Biomarkers
/
Immune Checkpoint Inhibitors
/
Immunotherapy
/
Neoplasms
Type of study:
Prognostic study
Limits:
Humans
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2020
Type:
Article
Similar
MEDLINE
...
LILACS
LIS