Research Advances of Human Homologue of Mouse Progressive Ankylosis Protein and Bone and Joint Diseases / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 293-299, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-878735
ABSTRACT
The human homologue of mouse progressive ankylosis protein(ANKH)is an inorganic pyrophosphate transport regulator,which regulates tissue mineralization by controlling the level of inorganic pyrophosphate.It plays an important role in the pathogenesis and development of bone and joint diseases,such as ankylosing spondylitis,craniometaphyseal dysplasia,and articular cartilage calcification.This review summarizes the progress of research on ANKH and the above-mentioned diseases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Hyperostosis
/
Hypertelorism
/
Joint Diseases
/
Ankylosis
/
Mutation
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2021
Type:
Article
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