Analysis of animal models of ulcerative colitis based on characteristics of clinical symptoms of traditional Chinese and Wes-tern medicine / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 757-761, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-878936
ABSTRACT
This article aims to provide a good experimental method for the study of drug treatment of ulcerative colitis. According to the characteristics of ulcerative colitis's clinical symptoms, common ulcerative colitis animal models were analyzed. Based on the characteristics of clinical symptoms of traditional Chinese medicine and Western medicine for ulcerative colitis disease, the existing commonly used animal models of ulcerative colitis were analyzed to summarize the current matching degree, advantages and disadvantages of the exi-sting animal models of ulcerative colitis and clinical symptoms. At present, studies on ulcerative colitis mainly adopt four types of induction modeling methods, such as immunization, chemical stimulation, compound method and gene model. There are many reported methods of colitis modeling, but no model can reflect the characteristics of clinical symptoms of ulcerative colitis treated with Western or Chinese medicine. This article summarizes the characteristics, clinically relevant symptoms and applicable scope of immunization, chemical stimulation, compound method, and gene model, so as to provide a reliable animal model for subsequent studies of prevention and treatment of colitis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Colitis, Ulcerative
/
China
/
Charadriiformes
/
Disease Models, Animal
/
Medicine
/
Medicine, Chinese Traditional
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Animals
Country/Region as subject:
Asia
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2021
Type:
Article
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