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One new cembranoid diterpene from gum resin of Boswellia carterii / 中国中药杂志
Article in Chinese | WPRIM | ID: wpr-879180
Responsible library: WPRO
ABSTRACT
This study aims to study the chemical components from the gum resin of Boswellia carterii. Five cembranoid diterpenes were isolated from the gum resin of B. carterii by various of column chromatographies including silica gel, Sephadex LH-20, and semi-preparative HPLC. Their structures were identified on the basis of physicochemical properties, mass spectrometry(MS), nuclear magnetic resonance(NMR), Ultraviolet(UV) and infrared(IR) spectroscopic data. These compounds were identified as(1S,2E,4R,5S,7E,11E)-4-methoxy-5-hydroxycembrane(1),(1R~*,4R~*,5E,8E,12E,15E)-4-hydroxycembra-5,8,12,15-tetraene(2), cembrene A(3),(3S,4S,7R)-4-hydroxycembrane(4), and pavidolide D(5). Compound 1 was a new compound. Compounds 2, 4, and 5 were obtained from the gum resin of B. carterii for the first time. Compound 2 showed weak inhibition on the human liver cancer cell line HepG2.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Resins, Plant / Humans / Molecular Structure / Cell Line / Boswellia / Diterpenes Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2021 Type: Article
Full text: Available Index: WPRIM (Western Pacific) Main subject: Resins, Plant / Humans / Molecular Structure / Cell Line / Boswellia / Diterpenes Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2021 Type: Article