Pregnancy-Induced Hemophagocytic Lymphohistiocytosis: A Case Report and Literature Review / 中国医学科学杂志(英文版)
Chinese Medical Sciences Journal
;
(4): 371-376, 2020.
Article
in English
| WPRIM
| ID: wpr-879300
ABSTRACT
Hemophagocytic lymphohistiocytosis (HLH) is a rare but devastating disease characterized by dysregulated immune response and hyperinflammation. To our knowledge, pregnancy-induced HLH has been rarely reported in the literature. A 30-year-old pregnant woman presented persistent fever for 21 days since 17 weeks of pregnancy. The possible etiologies such as infection, autoimmune disorder, and malignancy had been ruled out based on a series of exhaustive examinations. The disease progressed despite the use of broad-spectrum antibiotics and dexamethasone. The patient was diagnosed as pregnancy-induced HLH, and finally recovered completely after termination of pregnancy by caesarean and the continuous use of glucocorticoid which played a crucial part in controlling hyperinflammation. Pregnancy-induced HLH could be fatal if effective treatment was not initiated timely. Further studies are needed to improve early diagnosis and etiology identification of HLH.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Screening study
Language:
English
Journal:
Chinese Medical Sciences Journal
Year:
2020
Type:
Article
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