Intracerebroventricular drug administration
Translational and Clinical Pharmacology
;
: 117-124, 2017.
Article
in English
| WPRIM
| ID: wpr-87967
ABSTRACT
Among the various routes of drug administration, perhaps the least studied is intracerebroventricular (ICV) administration. This route has been shown to be particularly useful in administering to the central nervous system (CNS) drugs that do not cross the blood-brain barrier readily. As such, the ICV route is a valuable option for providing therapeutic CNS drug concentrations to treat patients with CNS infectious and neoplastic diseases. This route of drug administration also has the advantage of minimizing systemic toxicity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacokinetics
/
Blood-Brain Barrier
/
Central Nervous System
/
Meningitis
Limits:
Humans
Language:
English
Journal:
Translational and Clinical Pharmacology
Year:
2017
Type:
Article
Similar
MEDLINE
...
LILACS
LIS