Inhibition of indoxyl sulfate-induced intrarenal renin-angiotensin system activation: targeting the aryl hydrocarbon receptor
Translational and Clinical Pharmacology
;
: 114-116, 2017.
Article
in English
| WPRIM
| ID: wpr-87968
ABSTRACT
Indoxyl sulfate, a protein-bound uremic toxin, leads to CKD (chronic kidney disease) progression and its complications through the activation of AhR (aryl hydrocarbon receptor) and RAS (renin-angiotensin system). Inhibition of these pathways may slow the development of CKD and CKD-associated complications.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Renin-Angiotensin System
/
Receptors, Aryl Hydrocarbon
/
Renal Insufficiency, Chronic
/
Indican
/
Kidney
Language:
English
Journal:
Translational and Clinical Pharmacology
Year:
2017
Type:
Article
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