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Clinical features of children with Guillain-Barré syndrome and the significance of Brighton criteria / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics ; (12): 153-157, 2021.
Article in Chinese | WPRIM | ID: wpr-879826
ABSTRACT
OBJECTIVE@#To study the clinical features of children with Guillain-Barré syndrome (GBS) and the significance of Brighton criteria in childhood GBS.@*METHODS@#A retrospective analysis was performed on the medical data of 72 children with GBS. Brighton criteria were used for the grading of diagnostic certainty (level 1 as the highest level, and level 4 as the lowest level). A Spearman's rank correlation analysis was used to evaluate the correlation of auxiliary examinations with the level of diagnostic certainty of Brighton criteria.@*RESULTS@#A total of 72 children with GBS were enrolled, with a mean age of onset of (98±32) months. All children (100%, 72/72) had weakness of bilateral limbs and disappearance or reduction of tendon reflex, and limb weakness reached the highest level of severity within 4 weeks. Of all the 72 children, 68 (94%) had positive results of neural electrophysiological examination and 51 (71%) had positive results of cerebrospinal fluid (CSF) examination, and the positive rate of neural electrophysiological examination was significantly higher than that of CSF examination (@*CONCLUSIONS@#Most of the children with GBS meet Brighton criteria level 1, and the positive results of CSF examination and neural electrophysiological examination play an important role in improving the level of diagnostic certainty of Brighton criteria. Neural electrophysiological examination has a higher positive rate than CSF examination in the early stage of the disease.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Physical Examination / Retrospective Studies / Muscle Weakness / Guillain-Barre Syndrome / Extremities Type of study: Observational study Limits: Child / Child, preschool / Humans Language: Chinese Journal: Chinese Journal of Contemporary Pediatrics Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Physical Examination / Retrospective Studies / Muscle Weakness / Guillain-Barre Syndrome / Extremities Type of study: Observational study Limits: Child / Child, preschool / Humans Language: Chinese Journal: Chinese Journal of Contemporary Pediatrics Year: 2021 Type: Article