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Clinical features and prognosis of childhood acute myeloid leukemia with myelodysplasia-related changes / 中国当代儿科杂志
Article in Chinese | WPRIM | ID: wpr-879845
Responsible library: WPRO
ABSTRACT
OBJECTIVE@#To study the clinical features and prognosis of childhood acute myeloid leukemia with myelodysplasia-related changes (AML-MRC).@*METHODS@#A retrospective analysis was performed on the medical data of 14 children who were diagnosed with AML-MRC from June 2014 to March 2020, including clinical features, laboratory examination results, and prognosis.@*RESULTS@#Among the 14 children with AML-MRC, there were 9 boys and 5 girls, with a median age of 11 years (range 1-17 years), a median leukocyte count of 8.3×10@*CONCLUSIONS@#Childhood AML-MRC is often observed in boys, and AML-M5 is the most common type based on FAB classification. Such children tend to have a poor prognosis. HSCT is expected to improve the poor prognosis of children with AML-MRC. However due to the small number of cases, it is necessary to increase the number of cases for further observation.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Myelodysplastic Syndromes / Female / Humans / Male / Leukemia, Myeloid, Acute / Child / Child, Preschool / Retrospective Studies / Adolescent Language: Chinese Journal: Chinese Journal of Contemporary Pediatrics Year: 2021 Type: Article
Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Myelodysplastic Syndromes / Female / Humans / Male / Leukemia, Myeloid, Acute / Child / Child, Preschool / Retrospective Studies / Adolescent Language: Chinese Journal: Chinese Journal of Contemporary Pediatrics Year: 2021 Type: Article