Risk factors for neonatal congenital hypothyroidism: a Meta analysis / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 505-512, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-879885
ABSTRACT
OBJECTIVE@#To investigate the risk factors for congenital hypothyroidism (CH) in neonates, and to provide a reference for the prevention of CH.@*METHODS@#The databases including China Biomedical Literature Service System, China National Knowledge Infrastructure, Wanfang Data, and Weipu Periodical Database, PubMed, Web of Science, Embase, SpringerLink, and Elsevier/ScienceDirect were searched for studies on the risk factors for CH in neonates published up to August 1, 2020. R 3.6.2 and RevMan 5.3 software were used to perform a Meta analysis.@*RESULTS@#A total of 20 studies were included, with 13 case-control studies and 7 cross-sectional studies. There were 11 564 neonates in total, with 3 579 neonates in the case group and 7 985 neonates in the control group. The Meta analysis showed that advanced maternal age (@*CONCLUSIONS@#Advanced maternal age, gestational thyroid disease, gestational diabetes mellitus, anxiety, medication during pregnancy, radiation exposure during pregnancy, family history of thyroid disease, low birth weight, fetal macrosomia, preterm birth, post-term birth, twin pregnancy or multiple pregnancy, and birth defects may increase the risk of CH in neonates.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
China
/
Cross-Sectional Studies
/
Risk Factors
/
Congenital Hypothyroidism
/
Premature Birth
Type of study:
Etiology study
/
Observational study
/
Prevalence study
/
Risk factors
/
Systematic reviews
Limits:
Female
/
Humans
/
Infant, Newborn
/
Pregnancy
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2021
Type:
Article
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