Research advances in the role of ferroptosis in neonatal hypoxic-ischemic brain damage / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 536-541, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-879890
ABSTRACT
Neonatal hypoxic-ischemic brain damage (HIBD) remains an important cause of neonatal death and disability in infants and young children, but it has a complex mechanism and lacks specific treatment methods. As a new type of programmed cell death, ferroptosis has gradually attracted more and more attention as a new therapeutic target. This article reviews the research advances in abnormal iron metabolism, glutamate antiporter dysfunction, and abnormal lipid peroxide regulation which are closely associated with ferroptosis and HIBD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Brain
/
Hypoxia-Ischemia, Brain
/
Ferroptosis
/
Animals, Newborn
/
Neurons
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2021
Type:
Article
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