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Analysis on Death Cases in Children with Acute Lymphoblastic Leukemia Treated with the CCLG-ALL 2008 Protocol / 中国实验血液学杂志
Article in Chinese | WPRIM | ID: wpr-880138
Responsible library: WPRO
ABSTRACT
OBJECTIVE@#To retrospective analyze the reason of death in children with acute lymphoblastic leukemia (ALL) treated with CCLG-ALL 2008 protocol, and the experience was summarized in order to reduce the mortality.@*METHODS@#916 children diagnosed as ALL and accepted CCLG-ALL 2008 protocol from April 2008 to April 2015 in our hospital were enrolled, the dead cases in them were analyzed retrospectively.@*RESULTS@#169 children died, including 111 (65.7%) males and 58 (34.3%) females. Recurrence was the main reason of death. 150 (88.7%) children died due to recurrence, among them, 86 (57.3%) cases gave up directly. The second reason of death was infection. The main clinical sites of infection were concentrated in respiratory system and digestive system. Bacterial infection was most common (Gram-negative was common).@*CONCLUSION@#Enough finance and improving family compliance can decrease the mortality in children with ALL. Early rational use of antibiotics can reduce infection-related mortality in children with ALL.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Female / Humans / Male / Antineoplastic Combined Chemotherapy Protocols / Child / Retrospective Studies / Disease-Free Survival / Precursor Cell Lymphoblastic Leukemia-Lymphoma Language: Chinese Journal: Journal of Experimental Hematology Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Female / Humans / Male / Antineoplastic Combined Chemotherapy Protocols / Child / Retrospective Studies / Disease-Free Survival / Precursor Cell Lymphoblastic Leukemia-Lymphoma Language: Chinese Journal: Journal of Experimental Hematology Year: 2021 Type: Article