Prognostic Value of Interim / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 731-734, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-880140
ABSTRACT
OBJECTIVE@#To explore the value of interim @*METHODS@#Twenty-one patients with ENKTL who were pathologically diagnosed at Shanghai General Hospital of Nanjing Medical University (Shanghai General Hospital) from January 2015 to December 2018 were retrospectively collected, and @*RESULTS@#After treatment, 11 patients had complete remission (CR), 3 had partial remission (PR), 1 had stable disease (SD), and 6 had disease progression (PD). The CR patients' △SUVmax was significantly higher than non-CR patients [(66.07±22.33)% vs (36.87±23.28)%, t=2.927, P=0.009]. Calculated from the receiver operating curve (ROC), the optimal cut-off point of ΔSUVmax was 51.45%. The median follow-up time was 32 months. Kaplan-Meier survival analysis showed that KPI, DS and ΔSUVmax had significance in predicting PFS and OS (P<0.05). COX regression analysis showed that DS was an independent risk factor affecting PFS (P<0.05), and KPI and ΔSUVmax were independent risk factors affecting OS (P<0.05).@*CONCLUSION@#Interim
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
China
/
Retrospective Studies
/
Disease-Free Survival
/
Fluorodeoxyglucose F18
/
Lymphoma, Extranodal NK-T-Cell
/
Positron Emission Tomography Computed Tomography
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2021
Type:
Article
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